The Dangers of Synthetic Marijuana

by pharmacy on May 11, 2012

Synthetic marijuana: you may know it by such fanciful names as K2, Spice, Spike 99, Genie, Blaze, Red X Dawn, Purple Wave, Vanilla Sky, or Bliss. It’s legal…but is it also lethal?

 

Beginning in 2009, a dangerous substitute for marijuana began showing up across the U.S. – in conveniences stores, gas stations, head shops, at flea markets, online, and anywhere that things like incense are sold. Marketed as incense, powerful herbal products infused with designer drugs, the product is typically packaged in zip-top bags with psychedelic art on the labels.

 

The labels claim that the package contains only a mixture of herbs, but smoking only herbs would not produce the cannabis-like high induced by theses products…without any indication on a drug screen. At first, researchers were baffled. Then in late 2008, scientists at the University Hospital Freiburg, Germany discovered that the herbs were treated with at least two different synthetic cannabinoids.

 

In the brain, these synthetic cannabinoids resemble THC and stimulate CB1 cannabinoid receptors, producing a high similar to that of potent marijuana. But the chemical makeup of these synthetic drugs is much different than that of THC, and they have not been subjected to human testing and it’s unknown how long they may remain in the body. About 100 of these chemical agents have been synthesized and tested on animals. The drugs affect the parts of the brain that controls temperature, appetite, perception, memory, problem solving, the immune system, and hormone levels, among other things.

 

These drugs are particularly dangerous because the perception is that if they are sold over the counter, they must be safe. People, especially kids, don’t realize that the products are completely unregulated and untested. Since they are unregulated, the chemical composition can change from batch to batch, making each experience different, even when using the same product.

 

Emergency rooms and psychiatric wards are seeing the results. Some people just get high. Others wind up with full-blown psychosis that can last a month.

 

Several states have already followed Europe’s lead and banned the chemical components of Spice and other fake weed products, and more states are expected to follow suit. The DEA is closely monitoring the product and has banned some of the chemicals from use, but not all. One chemical listed by the DEA as a concern is HU-210. This chemical has been found to be up to 800 times more powerful than THC, and just as addictive.

 

The controversy over marijuana has been swirling for half a century, but the effects and dangerous of garden-variety weed don’t compare in any way to the products designed to mimic the real thing. What do you think? Should this product, in all its forms, be removed from the shelves everywhere? Some people argue against regulations, saying that we are already regulated to death in the U.S. Would this problem be solved by legalizing marijuana?

 

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While most teenage girls are researching the most flattering lipstick color, 17-year-old Monta Vista High School senior Angela Zhang was using bioengineering to find a cure for cancer. According to Zhang, her breakthrough is a “nanoparticle that’s kind of like the Swiss Army knife of cancer treatment in that it can detect cancer cells, eradicate the cancer cells and then monitor the treatment response.” Her goal was to create a personalized cancer treatment for a targeted approach. Her after school project won top honors at the 2011 Siemens Competition in Math, Science & Technology and a $100,000 scholarship.

 

The $100,000 scholarship team prize at the competition was taken by Ziyuan Liu and Cassee Cain, a pair of seniors at Oak Ridge High School in Oak Ridge, Tennessee who collaborated to transform an Xbox360 into a sensor that analyzes the gaits of amputees or joint replacement patients wearing prosthetics. Competition judge Sudeep Sarkar, a computer engineer at the University of South Florida, predicts that this technology could help prosthetic manufacturers design more efficient products and drastically reduce medical costs by allowing clinicians to perform diagnostics and monitor patient progress from anywhere. With telehealth rapidly becoming an accepted medical practice, expansion into prosthetic aftercare could lower costs and raise the quality of care for recovering patients.

In March, the Intel Science Talent Search awarded yet another innovative teenager, Nithin Tumma of Fort Gratiot, Michigan, a $100,000 scholarship for his work. He found a way to potentially slow the spread of cancer and decrease cancer malignancy by inhibiting specific proteins. In ninth place of the talent search, Alissa Zhang won a $20,000 award for devising a way to monitor diabetic glucose levels using body fluids other than blood, like tears or saliva…which would be a welcome relief for pincushion diabetics weary of needles and could lead to better compliance and more careful monitoring.

 

The Flying Monkeys, a group of middle school Girl Scouts from Ames, Iowa, won the 2011 Global Innovation Award sponsored by FIRST LEGO League and the X Prize Foundation with a prosthetic hand device they invented to help a little girl born with no fingers on her right hand. Due to the efforts of aspiring young engineers Gaby Dempsey, Mackenzie Gewell, and Kate Murray, the 3-year-old girl is able to write for the first time.

 

At the 2011 Google Science Fair, Shree Bose took first prize in the 17-18 age group for discovering a way to improve treatment for ovarian cancer patients who have developed resistance to some commonly prescribed chemotherapy drugs.

 

With such amazing accomplishments before they even leave school, these kids are sure to be the future rockstars of the scientific world. In a field traditionally dominated by men, the status quo is in grave danger from the next generation of women.

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This year’s Health Datapalooza will be held on June 5-6, at the Washington Convention Center in Washington, DC. The event will feature exciting new products, services, applications, and features based on open source health data. Entrepreneurs across the country are submitting their innovations to be judged by panels comprised of health care professionals, community leaders, and consumers. The best inventions will be showcased during the event. It’s an exciting opportunity for entrepreneurs and a great way for pharmacists to stay on top of the next big thing in the healthcare data industry.

 

Last year’s event demonstrations included:

 

  • Castlight Health debuted an app that allows the consumers and healthcare providers reduce healthcare costs by shedding light on the wide variations in cost, quality, and convenience options. This app puts healthcare information in the hands of the patient to help them make informed decisions about the best care at the most affordable price. Information includes plan benefits, deductible and other out-of-pocket costs, doctor, lab, and clinic options.
  • Healthagen’s iTriage connects symptoms, diseases, procedures, medications, treatment, with every nationwide healthcare provider for easy reference and quick diagnostic help. Users can enter symptoms, identify possible causes, and find an appropriate local doctor or healthcare provider.
  • Lumeris’ Maestro is a powerful program that allows plan providers, hospitals, medical groups, and individual physicians to identify opportunities and strategies to improve the quality and lower the cost of health care. This web software aggregates clinical and financial data and enhances collaboration between payers and health care providers.
  • The MedWatcher app (currently available for the iPhone and iPad) is designed to improve drug safety by providing current safety advisories with an interactive reporting tool for users to submit adverse reactions. This app could prove absolutely invaluable to pharmacists.
  • Ozioma is an online software designed to aggregate and disseminate local health information. Users can search for more than sixty reliable health sources—including the CDC-for easy-to-understand bytes to share with the public.

 

Speakers and programs

In addition to the debut of exciting new data products, Datapalooza will feature a number of programs and speakers, including keynote speakers: United States Chief Technology Officer Todd Park; HHS Secretary Kathleen Sebelius; the executive editor of Wired Magazine and author of The Decision Tree: Taking Control of Your Health in the New Era of Personalized Medicine Thomas Goetz; lung transplant surgeon and Senator Bill Frist; and the CEO of Aetna Inc., Mark Bertolini. A packed schedule includes other speakers, demonstrations, breakout sessions, and panel discussions.

For more information or to register, visit the Health Data Initiative Web page. It should be exciting to see the new and innovative products representing the future direction of healthcare.

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The Rise in Antidepressant Use Among Youth

by pharmacy on March 28, 2012

It’s no secret that today’s youth are under constant barrage from media, social networks, and society as a whole regarding how they should look, what they should feel, who they should date, and how they should handle their emotions. The downside to this is an alarming rate of depression, anxiety, and other mental illnesses in today’s young people. What this means for pharmaceutical companies is an unprecedented amount of clients that will be filling prescriptions for anxiety medications, SSRIs, and even scripts for anti-psychotic medications.

Treating these youth comes with a catch-22. Some of these medications cause well known and unwanted side effects such as weight gain, sexual dysfunction or loss of libido, acne, and more. In severe cases, use of antidepressants must be closely monitored by health care professionals due to the increase of suicidal tendencies in the youth taking the medication. How can pharmacies address the concerns of their clients that are experiencing some of these side effects? The answer to that is simple: Offer resources.

If space is available, display literature from local low-cost or sliding scale mental health clinics, sex therapists, and special interest support groups, for example: if such a thing exists in your local community, offer a pamphlet from a group for youth suffering from depression, anxiety, schizophrenia, and other mental health issues. The key to addressing the problems that come with the amount of young people that are on such medications is to make sure that they know they are not alone. Many youth are often bullied, and their mental health deteriorates if they feel that they are alienated in their community. Often times, this can result in a tragic (and preventable) loss of life. It is everyone’s to do what they can to reduce the amount of young people lost to the choice to take their own lives.

Another issue is the cost of such medications for homeless and alienated youth that may not have access to family or state funded health insurance. To prevent these young people from simply opting to “not take” their medication or live without it, a priority should be to display any information from your suppliers telling your clients how they can receive free or low cost medication. Most drug manufacturers offer some sort of program to those who are struggling to make ends meet, and to youth on a fixed income – often the choice between a vital necessity like the electric bill or medication comes up frequently. Offering these resources will make it more likely that your clients have the information available to reach out to their medication’s manufacturer to obtain their prescription for a cost that could make it affordable to them. These steps may seem small, but they can make a difference to today’s youth that is unmistakable.

Does your pharmacy have any special programs for young people who fill prescriptions for antidepressants?

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HIV, Hepatitis C, and other forms of sexually transmitted infections (STIs) are an ever-growing risk for today’s youth. As pharmacies, it is our responsibility to dispense medication to treat these conditions. However, taking it a step further has the chance to also help the communities in which we serve. Making personal connections with individual clients, organizations that provide care and education, and enabling staff to treat individuals and not just script numbers is the key to success and building relationships.

Training is in place to allow today’s youth in at-risk demographics (whether they are homeless, addicted to substances, LGBTQ, etc.) to assess the risks of another youth of contracting an STI, HIV, or Hepatitis. One of these programs is the Project Heart program, and it allows youth to be candid and open with one another while teaching safer sex practices, treatment management, and allows for community health clinics and initiatives to refer these clients to their practices and pharmacies for further testing or treatment.

In most pharmacies, flu shot clinics are commonplace. This has made flu shots more accessible to low income or at-risk individuals who can’t afford regular physician visits. If we were to reach out to our communities, homeless shelters, LGBT youth centers, and recovery homes – clinics could be started for STI screening, risk assessment, on site referrals, and more. This would enable people who perhaps do not have reliable transportation to get to an off-site clinic or testing center to be able to get to their local pharmacy and get valuable testing and care that they desperately need.

Locating resources for screenings, clinics, and testing is often as simple as conducting a search online or making a call. Chances are, local clinics and at-risk individual direct service organizations have approached your pharmacy before about assessments, shot clinics, and similar services. Now is the time to further these connections. This is something that is vital to communities, and most clinics will be glad to spread the word about your program, if not offer to help in some way. Getting others involved is the key to success.

Offering these services to not just at-risk individuals, but our communities as a whole can help increase our presence and enable our staff and management to connect with clients on a personal level. Bringing in staff from clinics to conduct screenings, risk assessment, referrals, rapid HIV testing, and more on-site can be beneficial to a number of people that might not want to go to a specialized center for fear of judgment or harassment. Opening pharmacy doors for this sort of program will allow people who might shy away from treatment to break down their own mental barriers, and improve or even save their lives in the process.

Does your pharmacy already offer clinics that cater to at-risk youth, or have you considered such a program? If so, have these clinics helped you attract a new customer demographic?

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Candy, Cigarettes, Morning After?

by pharmacy on March 7, 2012

Vending machines have carried all kinds of chips, snacks, drinks, and OTC pharmacy items, but the one located in the student health center at Shippensburg University in Pennsylvania raises the ante to a controversial new level. For a reasonable $25, students and faculty can buy a single dose of Plan B out of a dispenser.

The FDA is investigating to be sure the machine is complicit with laws, but the machine is located in an area inaccessible to the general public and the drug is over-the-counter. Since it will not abort an existing pregnancy and can only prevent pregnancy from starting, it is considered a contraceptive. Contrary to popular misinformation, it is not akin to an abortion pill.

Before making the decision to allow the dispenser, college administrators verified that every student on campus was over the minimum age required by law for purchase, 17. It’s not new, exactly; the machine has been in place for about two years. The story just recently hit the news, part of a storm of controversy over the Susan G. Komen Foundation’s decision to refuse funding to Planned Parenthood and the decision’s quick reversal under a backlash of public opinion, followed almost immediately by the Catholic Church’s objections to providing birth control to its employees through insurance.

OTC vending machines full of first aid supplies, along with condom and tampon dispensers, have been common since the fifties, when cigarette machines were equally common. Cigarette machines have become increasingly rare, since a vending machine cannot verify the age of the buyer. The age limit for Plan B pill raises similar concerns.

Shippensburg students seem to appreciate the machine. School proponents point out that rape victims might find a quick purchase at a machine less difficult than the shame associated with a trip to the drug store in the tiny town, but some wonder if the other side of the coin is that easy access to the drug may deter rape victims from seeking medical care. Not that rape victims are the only women who may choose to purchase the pill. It’s certainly too expensive to be used as a primary contraceptive, but things happen. Condoms break, pills are skipped, unexpected opportunities arise (no pun intended).

Plan B comes in a one-dose package that includes a single pill. Overdose or misuse is unlikely. What do you think? Good idea? Bad idea? There may be some merit to the argument that medicine dispensed by a machine does not come with human interaction to highlight warnings and side effects. Is that a valid reason to ban the machines? Are the objections…and the controversy…real, or is it all based on religion and politics?

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